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TRIS NAC STERILE OTOLOGICAL SOLUTION 120 ML
22% off
€18,39
€23,70
Unit price
/
Unavailable
Tax included, shipping and discounts calculated at checkout.
ICF | SKU:
975062908
TRIS NAC STERILE OTOLOGICAL SOLUTION 120 ML is backordered and will ship as soon as it is back in stock.
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TRIS NAC STERILE OTOLOGICAL SOLUTION 120 ML
€18,39
€23,70
Unit price
/
Unavailable
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Description
Description
TRIS NAC STERILE OTOLOGICAL SOLUTION 120 ML
Tris-NAC
Description
Sterile solution.
Highly hygienic Tris-EDTA + N-Acetyl Cysteine (NAC) buffer for dogs and cats.
Tris-EDTA (Ethylene Diammine Tetracetic Acid) has bactericidal activity on non-growing bacteria located within the biofilm ( Ciofu et al, 2017 ); in association with Tromethamine (Tris) it damages the bacterial cell walls and increases the penetration inside the bacterial membranes; it is well tolerated and not ototoxic; it acts in synergy with chlorhexidine ( Guardabassi et al, 2010 ). Recently, an in vitro work has demonstrated that Tris-EDTA is a more than effective support in the treatment of chronic cases of Pseudomonas otitis with the presence of potential biofilms combined with antibiotics ( Pye et al, 2014 ).
NAC is an N-acetylated derivative of the amino acid cysteine, has mucolytic action, therefore it disrupts the production of exopolysaccharides thus weakening the EPS matrix. It has been recently used in eight clinical studies as an adjuvant treatment to disrupt mature biofilm and prevent its formation and has demonstrated an excellent safety and efficacy profile.
The association of Tris-EDTA and NAC on the skin and in the ear before the application of topical products such as chlorhexidine, antibiotics, synthetic antimicrobial peptides, therefore allows an increase in the permeability of the mature biofilm and, consequently, its disintegration, effectively supporting the overcoming of the problem of resistance to the classic antibacterial therapeutic approach.
How to use
1. Apply pressure to the top of the bottle until the capsule breaks completely.
2. Shake the bottle.
3. Use the syringe inside the package to take the quantity to be used according to the instructions of the Veterinarian.
In the ear canal: irrigate adequately and massage at the base of the ear.
On the skin: spray until the affected area is completely soaked.
Repeat treatment as needed or as directed by your veterinarian.
Format
120 ml bottle.
Cod. PP3310001
Sterile solution.
Highly hygienic Tris-EDTA + N-Acetyl Cysteine (NAC) buffer for dogs and cats.
Tris-EDTA (Ethylene Diammine Tetracetic Acid) has bactericidal activity on non-growing bacteria located within the biofilm ( Ciofu et al, 2017 ); in association with Tromethamine (Tris) it damages the bacterial cell walls and increases the penetration inside the bacterial membranes; it is well tolerated and not ototoxic; it acts in synergy with chlorhexidine ( Guardabassi et al, 2010 ). Recently, an in vitro work has demonstrated that Tris-EDTA is a more than effective support in the treatment of chronic cases of Pseudomonas otitis with the presence of potential biofilms combined with antibiotics ( Pye et al, 2014 ).
NAC is an N-acetylated derivative of the amino acid cysteine, has mucolytic action, therefore it disrupts the production of exopolysaccharides thus weakening the EPS matrix. It has been recently used in eight clinical studies as an adjuvant treatment to disrupt mature biofilm and prevent its formation and has demonstrated an excellent safety and efficacy profile.
The association of Tris-EDTA and NAC on the skin and in the ear before the application of topical products such as chlorhexidine, antibiotics, synthetic antimicrobial peptides, therefore allows an increase in the permeability of the mature biofilm and, consequently, its disintegration, effectively supporting the overcoming of the problem of resistance to the classic antibacterial therapeutic approach.
How to use
1. Apply pressure to the top of the bottle until the capsule breaks completely.
2. Shake the bottle.
3. Use the syringe inside the package to take the quantity to be used according to the instructions of the Veterinarian.
In the ear canal: irrigate adequately and massage at the base of the ear.
On the skin: spray until the affected area is completely soaked.
Repeat treatment as needed or as directed by your veterinarian.
Format
120 ml bottle.
Cod. PP3310001